Degs1 delta 4-desaturase, sphingolipid 1 [ Mus musculus (house mouse) ] - Gene - Data resources

13244

Degs1 delta 4-desaturase, sphingolipid 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 13244)

Symbol: Degs1

Full name: delta 4-desaturase, sphingolipid 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Degs; Des1; Mdes

Summary: Enables retinol isomerase activity and sphingolipid delta-4 desaturase activity. Acts upstream of or within ceramide biosynthetic process and positive regulation of apoptotic process. Predicted to be located in mitochondrion. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human DEGS1 (delta 4-desaturase, sphingolipid 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in placenta adult (RPKM 57.5), kidney adult (RPKM 52.3) and 28 other tissues

Orthologs: human

Gene size: 6838bp

Exon count: 4