Full name: adenosine kinase

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: AK

Summary: This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

Expression: Ubiquitous expression in liver (RPKM 10.9), thyroid (RPKM 8.6) and 25 other tissues

Gene size: 558070bp

Exon count: 16