Full name: adenosine kinase

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: 2310026J05Rik; 5033405D03Rik; Ak

Summary: Enables adenosine kinase activity and deoxyadenosine kinase activity. Involved in AMP salvage; GMP salvage; and dAMP salvage. Acts upstream of or within dATP biosynthetic process and purine ribonucleoside salvage. Located in cytosol and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skeleton. Used to study fatty liver disease. Human ortholog(s) of this gene implicated in hypermethioninemia due to adenosine kinase deficiency. Orthologous to human ADK (adenosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in liver adult (RPKM 33.3), liver E18 (RPKM 24.2) and 21 other tissues

Gene size: 396016bp

Exon count: 14