Gadd45a growth arrest and DNA-damage-inducible 45 alpha [ Mus musculus (house mouse) ] - Gene - Data resources

13197

Gadd45a growth arrest and DNA-damage-inducible 45 alpha [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 13197)

Symbol: Gadd45a

Full name: growth arrest and DNA-damage-inducible 45 alpha

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Ddit1; GADD45

Summary: Enables promoter-specific chromatin binding activity. Involved in negative regulation of angiogenesis; negative regulation of blood vessel endothelial cell migration; and negative regulation of peptidyl-serine phosphorylation of STAT protein. Acts upstream of or within centrosome cycle; negative regulation of protein kinase activity; and regulation of cell cycle. Located in nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; heart; sensory organ; and tibialis anterior. Used to study systemic lupus erythematosus. Orthologous to human GADD45A (growth arrest and DNA damage inducible alpha). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in ovary adult (RPKM 73.1), liver E14 (RPKM 52.4) and 24 other tissues

Orthologs: human

Gene size: 2312bp

Exon count: 4