Ccr7 chemokine (C-C motif) receptor 7 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 12775)
Source: NCBI Gene (ID 12775)
Symbol: Ccr7
Full name: chemokine (C-C motif) receptor 7
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: CC-CKR-7; CCR-7; CD197; Cdw197; Cmkbr7; EBI1; Ebi1h
Summary: Enables C-C chemokine receptor activity. Involved in several processes, including positive regulation of immune response; positive regulation of leukocyte chemotaxis; and regulation of cytokine production. Acts upstream of or within chemotaxis; homeostasis of number of cells; and immune response. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; immune system; reproductive system; and white fat. Used to study Sjogren's syndrome. Orthologous to human CCR7 (C-C motif chemokine receptor 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in spleen adult (RPKM 74.8), thymus adult (RPKM 70.1) and 2 other tissues
Orthologs: human
Gene size: 10879bp
Exon count: 3