Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 [ Mus musculus (house mouse) ] - Gene - Data resources

12614

Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 12614)

Symbol: Celsr1

Full name: cadherin, EGF LAG seven-pass G-type receptor 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Adgrc1; Crsh; Scy; crash

Summary: Predicted to enable calcium ion binding activity. Involved in establishment of planar polarity and neural tube closure. Acts upstream of or within several processes, including Rho protein signal transduction; apical protein localization; and morphogenesis of an epithelium. Located in membrane. Is expressed in several structures, including blastocyst; central nervous system; epithelium; primitive streak; and renal cortex. Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human CELSR1 (cadherin EGF LAG seven-pass G-type receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in colon adult (RPKM 9.9), ovary adult (RPKM 9.8) and 18 other tissues

Orthologs: human

Gene size: 135466bp

Exon count: 37