Full name: cadherin 11

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Cad11; OSF-4

Summary: This gene encodes a type II classical cadherin and preproprotein that is proteolytically processed to generate a mature protein product. This protein product is an integral membrane protein that mediates calcium-dependent cell-cell adhesion, specifically in the context of bone development. Homozygous knockout mice for this gene exhibit impaired synovium development and reduced bone density. Multiple pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Aug 2015]

Expression: Biased expression in limb E14.5 (RPKM 39.5), CNS E11.5 (RPKM 18.9) and 14 other tissues

Gene size: 153399bp

Exon count: 15