ADD1 adducin 1 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 118)
Source: NCBI Gene (ID 118)
Symbol: ADD1
Full name: adducin 1
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: ADDA
Summary: Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. [provided by RefSeq, Aug 2017]
Expression: Ubiquitous expression in brain (RPKM 57.3), ovary (RPKM 51.1) and 25 other tissues
Orthologs: mouse
Gene size: 86219bp
Exon count: 20