Egln3 egl-9 family hypoxia-inducible factor 3 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 112407)
Source: NCBI Gene (ID 112407)
Symbol: Egln3
Full name: egl-9 family hypoxia-inducible factor 3
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 2610021G09Rik; Hif-p4h-3; Phd3; SM-20
Summary: Enables peptidyl-proline dioxygenase activity. Involved in regulation of cell population proliferation and regulation of neuron apoptotic process. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including gallbladder; genitourinary system; gut; skeletal musculature; and somite. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human EGLN3 (egl-9 family hypoxia inducible factor 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in small intestine adult (RPKM 16.9), stomach adult (RPKM 16.8) and 24 other tissues
Orthologs: human
Gene size: 24894bp
Exon count: 5