Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 110834)
Source: NCBI Gene (ID 110834)
Symbol: Chrna3
Full name: cholinergic receptor, nicotinic, alpha polypeptide 3
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: (a)3; A730007P14Rik; Acra-3; Acra3
Summary: Enables acetylcholine-gated cation-selective channel activity. Acts upstream of or within several processes, including activation of transmembrane receptor protein tyrosine kinase activity; behavioral response to nicotine; and chemical synaptic transmission. Is integral component of postsynaptic specialization membrane. Part of acetylcholine-gated channel complex. Is active in cholinergic synapse. Is expressed in several structures, including central nervous system; gut; myenteric nerve plexus; paravertebral ganglion; and retina. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in adrenal adult (RPKM 6.2), whole brain E14.5 (RPKM 4.2) and 11 other tissues
Orthologs: human
Gene size: 16446bp
Exon count: 6