Prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 108079)
Source: NCBI Gene (ID 108079)
Symbol: Prkaa2
Full name: protein kinase, AMP-activated, alpha 2 catalytic subunit
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 2310008I11Rik; A830082D05; AMPKalpha2
Summary: Enables AMP-activated protein kinase activity; chromatin binding activity; and histone serine kinase activity. Involved in several processes, including regulation of autophagy; regulation of organelle organization; and regulation of protein modification process. Acts upstream of or within several processes, including cellular response to prostaglandin E stimulus; cellular response to xenobiotic stimulus; and response to muscle activity. Located in several cellular components, including cytoplasmic stress granule; dendrite; and neuronal cell body. Is expressed in several structures, including brain; genitourinary system; gut; lung; and spinal cord. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PRKAA2 (protein kinase AMP-activated catalytic subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in heart adult (RPKM 10.8), kidney adult (RPKM 9.5) and 18 other tissues
Orthologs: human
Gene size: 80250bp
Exon count: 9