Full name: KLF transcription factor 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: EKLF; EKLF/KLF1

Summary: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009]

Expression: Restricted expression toward bone marrow (RPKM 14.0)

Gene size: 2780bp

Exon count: 3