Espl1 extra spindle pole bodies 1, separase [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 105988)
Source: NCBI Gene (ID 105988)
Symbol: Espl1
Full name: extra spindle pole bodies 1, separase
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Cerp; ESP1; PRCE; SSE
Summary: Enables cysteine-type peptidase activity. Acts upstream of or within homologous chromosome segregation; meiotic spindle organization; and mitotic sister chromatid segregation. Predicted to be active in cytoplasm; microtubule cytoskeleton; and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and respiratory system. Used to study breast cancer. Orthologous to human ESPL1 (extra spindle pole bodies like 1, separase). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in thymus adult (RPKM 11.7), testis adult (RPKM 11.0) and 19 other tissues
Orthologs: human
Gene size: 28105bp
Exon count: 31