Systematic identification of cell fate regulatory programs using a single-cell atlas of mouse development
Source: NCBI BioProject (ID PRJNA734777)
Source: NCBI BioProject (ID PRJNA734777)
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Project name: Systematic identification of cell fate regulatory programs using a single-cell atlas of mouse development
Description: We performed single-cell RNA sequencing (scRNA-seq) analysis to 10 mouse tissues belonging to seven age groups, ranging from early organ occurrence to mature adult stage (E10.5, E12.5, E14.5, neonatal, day 10, day 21 and adult), all together profiling in more than 500,000 cells. The profiled organs span diverse systems, including brain, heart, intestine, kidney, liver, lung, pancreas, stomach, testis and uterus.These data represent, to our knowledge, the first single-cell atlas of detailed mouse differentiation throughout development.Overall design: Microwell datasets for ten mouse tissues (brain, heart, intestine, kidney, liver, lung, pancreas, stomach, testis and uterus) covering 5 stages including E14.5, neonatal, 10d, 3w, 6-8w. Embryo datasets cover E10.5 and E12.5. Some mouse tissues are used from GSE108097.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Zhejiang University School of Medicine, Center for Stem Cell and Regenerative Medicine
Literatures
- PMID: 35817981
Last updated: 2021-06-03