Project name: Genome-wide transcriptomic data from Streptococcus agalactiae strain CNCTC 10/84 wild type and an allelic exchange isogenic mutant lacking the GntR-class putative transcription factor mrvR

Description: As part of a broader study to identify genes that contribute to fitness of the human pathobiont Streptococcus agalacitae (group B Streptococcus), we identified a GntR-class transcription factor, named mrvR, which contributes to bacterial persistence in human amniotic fluid and multipe virulence phenotypes. In order to understand the transcriptome of mrvR, whole-genome transcriptomic analysis was performed with wild type group B Streptococcus and an mrvR deletion mutant at three growth phases.Overall design: Wild type and mrvR knockout CNCTC 10/84 at early-log, late-log, and stationary growth; 2 independent samples per condition; 12 samples total.

Data type: Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: Medical

Last updated: 2021-02-02