3D interaction maps in wild-type and histone variant deletion mutants generated by chromosome conformation capture [Hi-C I]
Source: NCBI BioProject (ID PRJNA486752)
Source: NCBI BioProject (ID PRJNA486752)
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Project name: 3D interaction maps in wild-type and histone variant deletion mutants generated by chromosome conformation capture [Hi-C I]
Description: Interaction matrices were generated by applying in situ Hi-C to wild-type and deletion mutant trypanosomes.Overall design: DNA-DNA interactions were captured in situ in Trypansoma brucei nuclei, digested with MboI and re-ligated to obtain chimeric DNA molecules of previously interacting chromatin. The ligation products were purified and prepared for paired-end Illumina sequencing. Experiments were performed in duplicates for both the wild-type and the deletion mutant.
Data type: Other
Sample scope: Multiisolate
Relevance: Medical
Organization: Core Unit Systems Medicine, Medical Department, University of Würzburg
Literatures
- PMID: 30333624
Last updated: 2018-08-20