Fetal Brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate
Source: NCBI BioProject (ID PRJNA330665)
Source: NCBI BioProject (ID PRJNA330665)
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Project name: Macaca nemestrina
Description: ZIKV was inoculated (strain FSS13025, Cambodia 2010) subcutaneously at five separate locations on the forearms, each with 107 plaque-forming units (PFU) into a healthy pregnant pigtail macaque at 119 days gestation (~28 weeks human pregnancy) to test directly whether ZIKV causes fetal brain injury.Overall design: Brain tissues from dam and fetus at necropsy (day 43 post-inoculation) were sequenced. A pigtail macaque brain sample from the Non-Human Primate Reference Transcriptome Project (NHPRTR.org) was used as a control
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Immunology, University of Washington
Literatures
- PMID: 27618651
Last updated: 2016-07-20