Evaluation of covS polymorphisms on group A streptococcal global gene expression
Source: NCBI BioProject (ID PRJNA273454)

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Project name: Streptococcus sp. 'group A'
Description: We sought to determine how single amino acid changes in the active site of CovS autophosphorylation and subsequent phosphorylation of the response regulator CovR affect the gene expression profile of group A streptococcusOverall design: There were 6 strains analyzed, each in quadruplicate replicates: 1) wild-type GAS; 2) covS deletion strain; 3) covS with alanine at AA 280; 4) covS with valine at AA 281; 5) covS with valine at AA 284; 6) covS with alanine at AA 457
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: Infectious Diseases, MD Anderson Cancer Center
Literatures
  1. PMID: 25561708
Last updated: 2015-01-23
Statistics: 24 samples; 24 experiments; 24 runs