gRNA sequencing of mitochondrial RNA binding 'MRB' complexes in Trypanosoma brucei RNA editing
Source: NCBI BioProject (ID PRJNA248153)
Source: NCBI BioProject (ID PRJNA248153)
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Project name: Trypanosoma brucei brucei strain:Lister strain 427 29-13
Description: Mitochondrial mRNAs in kinetoplastids require extensive U-insertion/deletion editing that is directed by guide RNAs (gRNAs), and exhibits substrate and developmental stage-specificity by unsolved mechanisms. In this project we focus on compositionally related factors collectively known as the mitochondrial RNA-binding complex 1 (MRB1) or gRNA-binding complex (GRBC) that are suspected to be involved in regulation of mitochondrial mRNA editing and study their guide RNA compositions.
Data type: transcriptome
Sample scope: Monoisolate
Relevance: Medical
Organization: Texas A&M University
Literatures
- PMID: 24865612
Last updated: 2014-05-20