Anti-BRAF mutation drug resistance enhances EGFR expression in melanomas [methylation profiling]
Source: NCBI BioProject (ID PRJNA195562)
Source: NCBI BioProject (ID PRJNA195562)
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Project name: Homo sapiens
Description: We treated melanoma cells with BRAF mutation with BRAF inhibitor and screened for BRAF inhibitor resistant cells. We extracted DNA from parental cells and resistant cell lines. We compared the DNA methylation via Illumina 450K Methylation ArrayOverall design: Bisulphite converted DNA from the 4 specimens was hybridised to the Illumina Infinium 450k Human Methylation Beadchip
Data type: Epigenomics
Sample scope: Multiisolate
Relevance: Medical
Organization: John Wayne Cancer Institute
Literatures
- PMID: 25243790
Last updated: 2013-03-30