Hdac6 regulates Tip60-p400 function in stem cells (gene expression)
Source: NCBI BioProject (ID PRJNA181060)
Source: NCBI BioProject (ID PRJNA181060)
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Project name: Mus musculus
Description: To identify the functional role of Hdac6 in embryonic stem cells, we examined gene expression changes in mouse ES cells upon Tip60, Hdac6 and double knockdown.Overall design: Two biological replicates each for control (GFP), Tip60, Hdac6 and double KD in E14 mouse ESCs. Lentiviral-based shRNA was used and gene expression changes were determined 3 days after KD. The global gene expression profiles of Tip60, Hdac6 and double KD were compared to control KD cells.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Ghadiri, Chemistry, The Scripps Research Institute
Literatures
- PMID: 24302573
Last updated: 2012-11-09