Differential expression in Wn5a and vector transduced 4T1 cells. [RNA-Seq]
Source: NCBI BioProject (ID PRJNA178237)
Source: NCBI BioProject (ID PRJNA178237)
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Project name: Mus musculus
Description: A highly metastatic breast cancer cell line, 4T1, was used to generate stable Wnt5a expressing and vector only control cells. Cells were generated using lentivirus infection and selection with blasticidin. Expression of Wnt5a was confirmed using western blot. Cell behaviour was characterized. Wnt5a expressing cells exhibited reduced migration in a transwell assay and reduced metastasis in a tail vein injection assay. Growth was not significantly affected.Overall design: One sample of each condition.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Serra, Cell Biology, University of Alabama at Birmingham
Literatures
- PMID: 23484019
Last updated: 2012-10-23