Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer (aCGH data).
Source: NCBI BioProject (ID PRJNA177952)

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Project name: Mus musculus
Description: Transcriptional profiling of normal and tumorigenic mouse mammary tissue. Mouse genotypes consist of wildtype, MMTV-Met, MMTV-Met;Trp53fl/+;Cre, and Trp53fl/+;Cre.Overall design: Two-color common reference design. Samples consist of 4 normal tissues, 8 MMTV-Met tumors, 10 MMTV-Met;Trp53fl/+;Cre tumors, and 8 Trp53;Cre tumors.
Data type: Variation
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Michael Hallett, McGill Centre for Bioinformatics, McGill University
Literatures
  1. PMID: 23509284
Last updated: 2012-10-16