Distinct signal transduction pathways downstream of the (P)RR revealed by microarray and ChIP-chip analyses [Expt: ChIP-chip] - Project - Data resources

PRJNA172168

Distinct signal transduction pathways downstream of the (P)RR revealed by microarray and ChIP-chip analyses [Expt: ChIP-chip]
Source: NCBI BioProject (ID PRJNA172168)

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Project name: Homo sapiens

Description: We performed a set of microarray and chromatin-immunoprecipitation (ChIP)-chip experiments using siRNA against the (pro)renin receptor ((P)RR), stable overexpression of PLZF, the PLZF translocation inhibitor genistein and the specific V-ATPase inhibitor bafilomycin to dissect transcriptional pathways downstream of the (P)RR.Overall design: In this dataset, we include the ChIP-chip data obtained from PLZF overexpressing KELLY cells, from PLZF overexpressing HEK293T cells and from KELLY as well as HEK293T cells both stably transfected with an insertless control vector.

Data type: Epigenomics

Sample scope: Multiisolate

Relevance: Medical

Organization: AG Heiko Funke-Kaiser, Center for Cardiovascular Research, Charité

Literatures

PMID: 23469216

Last updated: 2012-08-08