Project name: Trypanosoma brucei

Description: T. brucei PF cells were treated with several chemical reagents and anti-trypanosomatid drugs. The effect of each chemical perturbation on the transcriptome of T. brucei was examined by transcript profiling of treated vs. control cells. The results indicated widespread changes, suggesting that the transcriptome of T. brucei is highly responsive to environmental factors that perturb its metabolic and biological pathways.Overall design: 11 chemical perturbations, each co-hybridized with a common reference RNA from control non-treated cells. One array per treatment.

Data type: Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: Medical

Release date: 2012-05-30

Last updated: 2012-04-25