Project name: Homo sapiens

Description: Analysis of alternative activation of macrophages at gene expression level. The study forms part of a wider study where we compare the effects of IL-4 in different human and mouse macrophages. Our results support the notion that in vitro culture conditions greatly affect the macrophage response to IL-4.Overall design: Total RNA obtained from human monocyte derived macrophages upon exposure to 20 ng/ml of IL-4 for 24 hours. Monocytes were induced to mature into macrophages using X Vivo 10 medium supplemented with 1% autologous serum.

Data type: Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: Medical

Last updated: 2012-01-30