Dynamics of Sox2 and Esrrb occupancy during the differentiation of embryonic stem cells into trophoblast stem cells.
Source: NCBI BioProject (ID PRJNA143235)
Source: NCBI BioProject (ID PRJNA143235)
0 0
Project name: Mus musculus
Description: To understand the mechanism underlying the versatility in transcriptional regulation by Sox2 and Esrrb, we compared genome-wide binding sites of Sox2 and Esrrb in embryonic stem (ES) cells and trophoblast stem (TS) cells by chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq).Overall design: A tetracycline-inducible Oct3/4 knockout ES cell line ZHBTc4 was treated with Tet for 4 days in the presence of FGF4 and mouse embryonic fibroblasts (MEFs).
Data type: Epigenomics
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Bioinformatics Research Unit, Center for Biosystems Dynamics Research, RIKEN
Literatures
- PMID: 24120664
Last updated: 2011-04-07