Induction of trophoblast stem cells from embryonic stem cells by forced repression of Oct3/4.
Source: NCBI BioProject (ID PRJNA143233)
Source: NCBI BioProject (ID PRJNA143233)
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Project name: Mus musculus
Description: To characterize the transdifferentiation of embryonic stem (ES) cells into trophoblast stem (TS) cells triggered by forced repression of Oct3/4, we performed whole-genome expression analysis after tetracycline (Tet)-induced knockout of Oct3/4.Overall design: A Tet-inducible Oct3/4 knockout ES cell line ZHBTc4 was treated with Tet for 4 days in the presence of FGF4 and mouse embryonic fibroblasts (MEFs). A total of 21 samples from Day 0 to Day 4 were analyzed in three biological replicates.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Bioinformatics Research Unit, Advanced Center for Computing and Communication, RIKEN
Literatures
- PMID: 24120664
Last updated: 2011-04-07