SMAD1/5 binding regions of human pulmonary arterial smooth muscle cells (PASMCs) treated with BMP
Source: NCBI BioProject (ID PRJNA143115)
Source: NCBI BioProject (ID PRJNA143115)
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Project name: Homo sapiens
Description: Smad1/5 are transcription factors that engage in BMP-induced transcription. We determined and analyzed Smad1/5 binding sites by ChIP-sequencing. We used expression microarrays to compare the Smad1/5 binding sites identified by ChIP-seq to BMP-induced gene expressions.Overall design: PASMCs were treated with BMP for 1.5 h, and anti-SMAD1/5 ChIP-seq analyses were performed using the Illumina Genome Analyzer II.
Data type: Epigenomics
Sample scope: Multiisolate
Relevance: Medical
Organization: Molecular Pathology, University of Tokyo
Literatures
- PMID: 21764776
Release date: 2011-07-16
Last updated: 2011-04-25