Paternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammals (Affymetrix)
Source: NCBI BioProject (ID PRJNA142461)

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Project name: Mus musculus
Description: Epigenetic information can be inherited through the mammalian germline, and represents a plausible transgenerational carrier of environmental information. To test whether transgenerational inheritance of environmental information occurs in mammals, we carried out an expression profiling screen for genes in mice that responded to paternal diet.Characterising the change in RNA expression in sperm in response to different paternal diets.Overall design: Examination of the effect of different diets, control diet, low-protein diet and caloric-restriction diet, on the RNA expression in the sperm. 8 samples: 3 are control diets and 2 are low protein diets 1 caloric restriction diet, and 2 samples from Epidydimal tissue.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Friedman, Computer Scince, Hebrew University
Literatures
  1. PMID: 21183072
Release date: 2011-01-14
Last updated: 2010-12-07