Entamoeba histolytica genome sequencing project
Source: NCBI BioProject (ID PRJNA142)

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Project name: Entamoeba histolytica HM-1:IMSS
Description: Entamoeba histolytica (strain HM-1:IMSS), was the first human amoeba to have its genome sequenced, assembled and analyzed. Whole genome shotgun sequencing with small insert libraries was used to carry out sequencing to a 12.5-fold coverage. The sequencing project was a collaborative effort between JCVI (TIGR) and The Sanger Institute.The exact number of chromosomes in E. histolytica is uncertain due to difficulties in condensing and resolving them by pulse-field gel electrophoresis. Approximately 9,938 predicted genes with an average size of 1.17 kb, comprise 49% of the genome. One third of this organism's predicted proteins (31.8%) do not have identifiable sequence homologues in other species. The whole genome shotgun sequence data from E. histolytica strain HM-1:IMSS has been deposited in GenBank. The current version of the project (02) has the accession number AAFB02000000, consists of 1529 scaffolds DS571145-DS572673 and represents 8x coverage of the genome.This sequencing project was completed by a collaboration between JCVI (TIGR) and the Sanger Institute.
Data type: Genome sequencing and assembly
Sample scope: Monoisolate
Organization: J. Craig Venter Institute (TIGR); The Sanger Institute
Related RefSeq project: PRJNA19739
Literatures
  1. PMID: 15729342
  2. PMID: 20559563
Release date: 2004-12-09
Last updated: 2003-02-25
Statistics: 1 sample