Effect of SAICAR accumulation on global transcription
Source: NCBI BioProject (ID PRJNA114101)

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Project name: Saccharomyces cerevisiae
Description: We investigated the effects of SAICAR accumulation on transcriptional regulation of purine biosynthesis and other metabolic pathways. These data were compared to those obtained in the ade16ade17 vs WT comparison to determine the effects associated to accumulation of SAICAR alone. In this work, global transcription analyses were combined to measurements of intracellular nucleotides pools by HPLC.Keywords: Comparative genomic transcription analysis on total RNA from cells accumulating or not SAICAR.Overall design: One biological sample in dye swap
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Plateforme transcriptome, Biologie, Ecole Normale Supérieure
Literatures
  1. PMID: 19528318
Release date: 2009-05-15
Last updated: 2008-10-14