Effect of AICAR and SAICAR accumulation on global transcription (first part)
Source: NCBI BioProject (ID PRJNA114097)
Source: NCBI BioProject (ID PRJNA114097)
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Project name: Saccharomyces cerevisiae
Description: We investigated the effects of AICAR and SAICAR accumulation on transcriptional regulation of purine biosynthesis and other metabolic pathways. In this work, global transcription analyses were combined to measurements of intracellular nucleotides pools by HPLC.Keywords: Comparative genomic transcription analysis on total RNA from cells accumulating or not AICAR and SAICAR nucleotide derivatives.Overall design: One biological sample in dye swap
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Plateforme transcriptome, Biologie, Ecole Normale Supérieure
Release date: 2009-05-15
Last updated: 2008-10-14