Identification of a novel virulence related genome modification by comparative genomics of Entamoeba histolytica Japanese clinical isolates.
Source: NCBI BioProject (ID PRJDB4371)
Source: NCBI BioProject (ID PRJDB4371)
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Project name: Entamoeba histolytica
Description: Entamoeba histolytica is a causative agent of amebiasis. Disease state of amebiasis varies from asymptomatic to intestinal and extra-intestinal diseases. It is considered that there are factor that define the symptom, however, the molecular basis is not well understood. To approach this question, we conducted a comparative genomic analysis of two Japanese clinical isolates from asymptomatic and diarrheal disease patients. We found two genomic regions which are deleted in asymptomatic strain.
Data type: Genome sequencing
Sample scope: Monoisolate
Organization: Laboratory of Bacterial Genomics, Pathogen Genomics Center, National Institute of Infectious Diseases
Literatures
- PMID: 29554130
Release date: 2018-03-01
Last updated: 2015-11-19