Project name: Neo-antigen Discovery of Cancer Immunotherapy

Description: Tumor-specific antigens (TSAs) are highly desirable targets for cancer immunotherapy. However, current clinical studies have predominantly focused on neoantigens present in exon regions, while the limited number of TSAs identified from coding regions has impeded the development and application of immunotherapy. Here, we developed a proteogenomic approach that integrates multi-omics data from the whole genome, transcriptome, and immunopeptidome to globally discover TSAs.

Data type: Raw sequence reads; Genome sequencing; Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: Medical

Release date: 2023-11-14

Last updated: 2023-10-31

Data size: 4.25TB