Characterization of the 6'-N-aminoglycoside acetyltransferase gene aac(6')-Iq from the integron of a natural multiresistance plasmid.
Antimicrob Agents Chemother, 1998/6;42(6):1506-8.
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PMID: 9624504
Impact factor: 5.938
Abstract
The nucleotide sequence of a newly identified amikacin resistance gene, aac(6')-Iq (551 bp), is reported. It has 68.4 and 94.4% homology with the aac(6')-Ia gene and the recently described aac(6')-Ip gene, respectively. Analysis of its flanking sequences indicated that it is in the first cassette of a class I integron and has an attC site (59-base element) 108 bp in length.
MeSH terms
Acetyltransferases; Amikacin; Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; Drug Resistance, Multiple; Klebsiella pneumoniae; Molecular Sequence Data; Plasmids; Sequence Alignment; Sequence Homology, Amino Acid
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