A replication region of the IncHI plasmid, R27, is highly homologous with the RepFIA replicon of F.
Mol Microbiol, 1988/3;2(2):219-25.
Saul D[1], Lane D, Bergquist PL
Affiliations
PMID: 3288833
Impact factor: 3.979
Abstract
A region of the IncHI plasmid R27 has been found to share very close nucleotide sequence homology with the RepFIA replicon of F. This region has been located on a 1.6 kb segment of R27 plasmid DNA, and corresponds to ori-2 and the E gene of F. The incC repeat sequence region shows reduced homology, with the F repeats being an imperfect subset of a larger repeated sequence found in R27. The E gene homologue of R27 is able to initiate replication from the F ori-2 sequence and to repress the E gene promoter of F. The results are consistent with the observed incompatibility behaviour of R27, and have a bearing on the specificity of interaction of E protein with its DNA-binding sites.
MeSH terms
Amino Acid Sequence; Base Sequence; DNA Replication; Escherichia coli; Genes, Bacterial; Molecular Sequence Data; Plasmids; Replicon; Sequence Homology, Nucleic Acid
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