Identification of a transcriptional regulator for oligotrophy-responsive promoter in Rhodococcus erythropolis N9T-4.
Biosci Biotechnol Biochem, 2020/04;84(4):865-868.
Ikegaya R[1], Shintani M[1], Kimbara K[1], Fakuda, Masao, Yoshida N[1]
Affiliations
PMID: 31884880DOI: 10.1080/09168451.2019.1709792
Impact factor: 2.337
Abstract
Two genes, aldA, and mnoA, encoding an NAD-dependent aliphatic dehydrogenase and N,N'-dimethyl-4-nitrosoaniline-dependent methanol dehydrogenase, respectively, are strongly expressed when Rhodococcus erythropolis N9T-4 is grown under oligotrophic conditions. In this study, we found a transcriptional regulator required for the transcription of both aldA and mnoA. The transcriptional regulator was also found to be essential for the oligotrophic growth of N9T-4.
Keywords: Rhodococcus erythropolis; aldehyde dehydrogenase; methanol dehydrogenase; oligotrophy; transcriptional regulator
MeSH terms
Gene Expression Regulation, Bacterial; Promoter Regions, Genetic; Rhodococcus; Transcription, Genetic
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