camR, a negative regulator locus of the cytochrome P-450cam hydroxylase operon.
J Bacteriol, 1986/6;166(3):1089-95.
Koga H, Aramaki H, Yamaguchi E, Takeuchi K, Horiuchi T, Gunsalus IC
PMID: 3011733
Impact factor: 3.476
Abstract
A 4.27-kilobase insert from a HindIII DNA library of Pseudomonas putida carrying the CAM plasmid allowed coordinate expression of genes camD and camC under control of camR, an upstream regulator. The camC gene specifies cytochrome P-450cam, and camD specifies the 5-exo-alcohol dehydrogenase. A 1.38-kilobase deletion from the insert results in the constitutive expression of genes camC and camD; transformation in trans restores the substrate control, indicating that camR is a negative regulator.
MeSH terms
Alcohol Dehydrogenase; Alcohol Oxidoreductases; Amino Acid Sequence; Base Sequence; Chromosome Deletion; Cytochrome P-450 Enzyme System; DNA Restriction Enzymes; Deoxyribonuclease HindIII; Gene Expression Regulation; Genes; Genes, Bacterial; Genes, Regulator; Isoenzymes; Operon; Plasmids; Pseudomonas
More resources
Full text:
Europe PubMed Central; PubMed Central
EndNote: Download