Home
/
Data resources
/
Literature
/
29357812
The invasive MED/Q Bemisia tabaci genome: a tale of gene loss and gene gain.

BMC Genomics, 2018/01/22;19(1):68.

Xie W[1], Yang X[1], Chen C[2], Yang Z[1], Guo L[1], Wang D[2], Huang J[2], Zhang H[2], Wen Y[1], Zhao J[2], Wu Q[1], Wang S[1], Coates BS[3], Zhou X[4], Zhang Y[5]

Affiliations

PMID: 29357812DOI: 10.1186/s12864-018-4448-9

Impact factor: 4.547

Abstract
background: Sweetpotato whitefly, Bemisia tabaci MED/Q and MEAM1/B, are two economically important invasive species that cause considerable damages to agriculture crops through direct feeding and indirect vectoring of plant pathogens. Recently, a draft genome of B. tabaci MED/Q has been assembled. In this study, we focus on the genomic comparison between MED/Q and MEAM1/B, with a special interest in MED/Q's genomic signatures that may contribute to the highly invasive nature of this emerging insect pest.
results: The genomes of both species share similarity in syntenic blocks, but have significant divergence in the gene coding sequence. Expansion of cytochrome P450 monooxygenases and UDP glycosyltransferases in MED/Q and MEAM1/B genome is functionally validated for mediating insecticide resistance in MED/Q using in vivo RNAi. The amino acid biosynthesis pathways in MED/Q genome are partitioned among the host and endosymbiont genomes in a manner distinct from other hemipterans. Evidence of horizontal gene transfer to the host genome may explain their obligate relationship. Putative loss-of-function in the immune deficiency-signaling pathway due to the gene loss is a shared ancestral trait among hemipteran insects.
conclusions: The expansion of detoxification genes families, such as P450s, may contribute to the development of insecticide resistance traits and a broad host range in MED/Q and MEAM1/B, and facilitate species' invasions into intensively managed cropping systems. Numerical and compositional changes in multiple gene families (gene loss and gene gain) in the MED/Q genome sets a foundation for future hypothesis testing that will advance our understanding of adaptation, viral transmission, symbiosis, and plant-insect-pathogen tritrophic interactions.

Keywords: Bemisia tabaci; Detoxification enzymes; Gene gain and loss; Genome; Invasive species; MED/Q; Symbiosis

MeSH terms
Animals; Crops, Agricultural; Cytochrome P-450 Enzyme System; Genome, Insect; Glucuronosyltransferase; Hemiptera; Host Specificity; Insect Proteins; Insecticide Resistance; Multigene Family; Phylogeny; Symbiosis; Transcriptome
More resources
EndNote: Download