Whole-genome sequencing confirms that Burkholderia pseudomallei multilocus sequence types common to both Cambodia and Australia are due to homoplasy.
J Clin Microbiol, 2015/1;53(1):323-6.
De Smet B[1], Sarovich DS[2], Price EP[3], Mayo M[3], Theobald V[3], Kham C[4], Heng S[5], Thong P[4], Holden MT[6], Parkhill J[7], Peacock SJ[8], Spratt BG[9], Jacobs JA[10], Vandamme P[11], Currie BJ[3]
Affiliations
PMID: 25392354DOI: 10.1128/JCM.02574-14
Impact factor: 11.677
Abstract
Burkholderia pseudomallei isolates with shared multilocus sequence types (STs) have not been isolated from different continents. We identified two STs shared between Australia and Cambodia. Whole-genome analysis revealed substantial diversity within STs, correctly identified the Asian or Australian origin, and confirmed that these shared STs were due to homoplasy.
MeSH terms
Australia; Bacterial Typing Techniques; Burkholderia pseudomallei; Cambodia; Evolution, Molecular; Genome, Bacterial; Humans; Melioidosis; Multilocus Sequence Typing; Phylogeny
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