[Optimization of preparation technology of LIUWEI cataplasm, a kind of Zhuang national herbs].
Zhong Yao Cai, 2013/10;36(10):1694-7.
PMID: 24761682
Abstract
objective: To optimize preparation process of liuwei cataplasm, a Zhuang folk medical herb popularly applied as a kind of rheumatism, rheumatoid drug in Guangxi Zhuang Autonomous Region.
methods: Orthogonal design test was employed to optimise matrix proportion and molding technology of liuwei cataplasma with glossiness, adhesive power, matrix residue, skin following and repeatedly exposing as indexes.
results: Optimum matrix ratio of PANA, pressure sensitive adhesive, CNC-Na, gelatin, dihydroxyaluminium aminoacetate and glycerol was 0.5:1.0:0.4:0.1:0.3:3.0. Optimized parameters of technology were as follows: stiring speed 600 r/min, refining temperature 60 degrees C and drug loading of Liuwei extract 13.04%.
conclusion: Optimized liuwei cataplasm has a good adhesive power, exipcients and glossiness, meanwhile drug loading is large and no skin residue. The process is simple, stable and viable.
MeSH terms
Adhesiveness; Anti-Inflammatory Agents; Carboxymethylcellulose Sodium; Chemistry, Pharmaceutical; Drug Compounding; Drugs, Chinese Herbal; Gelatin; Glycerol; Medicine, Chinese Traditional; Ointments; Plants, Medicinal
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