Complete genome sequence of Streptococcus agalactiae strain SA20-06, a fish pathogen associated to meningoencephalitis outbreaks.

Stand Genomic Sci, 2013;8(2):188-97.

Pereira Ude P[1], Rodrigues Dos Santos A, Hassan SS, Aburjaile FF, Soares Sde C, Ramos RT, Carneiro AR, Guimarães LC, Silva de Almeida S, Diniz CA, Barbosa MS, Gomes de Sá P, Ali A, Bakhtiar SM, Dorella FA, Zerlotini A, Araújo FM, Leite LR, Oliveira G, Miyoshi A, Silva A, Azevedo V, Figueiredo HC

Affiliations

PMID: 23991251DOI: 10.4056/sigs.3687314

Abstract
Streptococcus agalactiae (Lancefield group B; GBS) is the causative agent of meningoencephalitis in fish, mastitis in cows, and neonatal sepsis in humans. Meningoencephalitis is a major health problem for tilapia farming and is responsible for high economic losses worldwide. Despite its importance, the genomic characteristics and the main molecular mechanisms involved in virulence of S. agalactiae isolated from fish are still poorly understood. Here, we present the genomic features of the 1,820,886 bp long complete genome sequence of S. agalactiae SA20-06 isolated from a meningoencephalitis outbreak in Nile tilapia (Oreochromis niloticus) from Brazil, and its annotation, consisting of 1,710 protein-coding genes (excluding pseudogenes), 7 rRNA operons, 79 tRNA genes and 62 pseudogenes.

Keywords: Streptococcus agalactiae; fish pathogen; genome sequencing

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