Prevalence and plasmid characterization of the qnrD determinant in Enterobacteriaceae isolated from animals, retail meat products, and humans.
Microb Drug Resist, 2013/8;19(4):331-5.
Zhang S[1], Sun J, Liao XP, Hu QJ, Liu BT, Fang LX, Deng H, Ma J, Xiao X, Zhu HQ, Liu YH
Affiliations
PMID: 23557071DOI: 10.1089/mdr.2012.0146
Impact factor: 2.706
Abstract
qnrD, unlike other qnr genes, is mainly located on small nonconjugative plasmids. We investigated the presence of qnrD among 1,373 Enterobacteriaceae isolates in China. Twelve qnrD-positive strains were detected, and all were nonsusceptible to fluoroquinolones. The complete sequence of plasmids showed that the qnrD determinants were located on two plasmids with a respective size of ~4.2 and 2.7 k-bp. Interestingly, the identification of qnrD in this study revealed the highest prevalence of Proteeae among Enterobacteriaceae identified.
MeSH terms
Animals; Animals, Domestic; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Typing Techniques; China; Conjugation, Genetic; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli Proteins; Fluoroquinolones; Humans; Meat Products; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids
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