AtWRKY15 perturbation abolishes the mitochondrial stress response that steers osmotic stress tolerance in Arabidopsis.
Proc Natl Acad Sci U S A, 2012/12/04;109(49):20113-8.
Vanderauwera S[1], Vandenbroucke K, Inzé A, van de Cotte B, Mühlenbock P, De Rycke R, Naouar N, Van Gaever T, Van Montagu MC, Van Breusegem F
Affiliations
PMID: 23169634DOI: 10.1073/pnas.1217516109
Impact factor: 12.779
Abstract
Environmental stresses adversely affect plant growth and development. A common theme within these adverse conditions is the perturbation of reactive oxygen species (ROS) homeostasis. Here, we demonstrate that the ROS-inducible Arabidopsis thaliana WRKY15 transcription factor (AtWRKY15) modulates plant growth and salt/osmotic stress responses. By transcriptome profiling, a divergent stress response was identified in transgenic WRKY15-overexpressing plants that linked a stimulated endoplasmic reticulum-to-nucleus communication to a disrupted mitochondrial stress response under salt-stress conditions. We show that mitochondrial calcium-flux sensing might be important for regulating an active mitochondrial retrograde signaling and launching an appropriate defense response to confer salt-stress tolerance.
MeSH terms
Adaptation, Physiological; Arabidopsis; Arabidopsis Proteins; Calcium; Flow Cytometry; Gene Expression Profiling; Hydrogen Peroxide; Microarray Analysis; Mitochondria; Mutagenesis, Site-Directed; Osmotic Pressure; Real-Time Polymerase Chain Reaction; Salinity; Stress, Physiological; Transcription Factors
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