Phylogenetic analysis of non-O157 Shiga toxin-producing Escherichia coli strains by whole-genome sequencing.
J Clin Microbiol, 2012/12;50(12):4123-7.
Ju W[1], Cao G, Rump L, Strain E, Luo Y, Timme R, Allard M, Zhao S, Brown E, Meng J
Affiliations
PMID: 23052305DOI: 10.1128/JCM.02262-12
Impact factor: 11.677
Abstract
Non-O157 Shiga toxin-producing Escherichia coli (STEC) strains are emerging food-borne pathogens causing life-threatening diseases and food-borne outbreaks. A better understanding of their evolution provides a framework for developing tools to control food safety. We obtained 15 genomes of non-O157 STEC strains, including O26, O111, and O103 strains. Phylogenetic trees revealed a close relationship between O26:H11 and O111:H11 and a scattered distribution of O111. We hypothesize that STEC serotypes with the same H antigens might share common ancestors.
MeSH terms
Cluster Analysis; Escherichia coli Infections; Foodborne Diseases; Genome, Bacterial; Humans; Molecular Epidemiology; Phylogeny; Sequence Analysis, DNA; Sequence Homology; Shiga-Toxigenic Escherichia coli
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