Cobalt sensitization and dermatitis: considerations for the clinician.
Dermatitis, 2012/9-2012/10;23(5):203-9.
Thyssen JP[1]
Affiliations
PMID: 23010826
Impact factor: 4.867
Abstract
This clinical review article presents clinical and scientific data on cobalt sensitization and dermatitis. It is concluded that cobalt despite being a strong sensitizer and a prevalent contact allergen to come up on patch testing should be regarded as a very complex metal to test with. Exposure data together with clinical data from metal workers heavily exposed to cobalt suggest that patch-test reactions are sometimes false positive and that patch testers should carefully evaluate their clinical relevance.
MeSH terms
Cobalt; Cross Reactions; Dermatitis, Allergic Contact; False Positive Reactions; Food; Humans; Manufactured Materials; Nickel; Occupational Exposure; Patch Tests; Prostheses and Implants
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