Genome sequence of the thermophilic strain Bacillus coagulans 2-6, an efficient producer of high-optical-purity L-lactic acid.

J Bacteriol, 2011/9;193(17):4563-4.

Su F[1], Yu B, Sun J, Ou HY, Zhao B, Wang L, Qin J, Tang H, Tao F, Jarek M, Scharfe M, Ma C, Ma Y, Xu P

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PMID: 21705584DOI: 10.1128/JB.05378-11

Impact factor: 3.476

Abstract
Bacillus coagulans 2-6 is an efficient producer of lactic acid. The genome of B. coagulans 2-6 has the smallest genome among the members of the genus Bacillus known to date. The frameshift mutation at the start of the d-lactate dehydrogenase sequence might be responsible for the production of high-optical-purity l-lactic acid.
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