Genome sequence of Staphylococcus lugdunensis N920143 allows identification of putative colonization and virulence factors.
FEMS Microbiol Lett, 2011/9;322(1):60-7.
Heilbronner S[1], Holden MT, van Tonder A, Geoghegan JA, Foster TJ, Parkhill J, Bentley SD
Affiliations
PMID: 21682763DOI: 10.1111/j.1574-6968.2011.02339.x
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Abstract
Staphylococcus lugdunensis is an opportunistic pathogen related to Staphylococcus aureus and Staphylococcus epidermidis. The genome sequence of S. lugdunensis strain N920143 has been compared with other staphylococci, and genes were identified that could promote survival of S. lugdunensis on human skin and pathogenesis of infections. Staphylococcus lugdunensis lacks virulence factors that characterize S. aureus and harbours a smaller number of genes encoding surface proteins. It is the only staphylococcal species other than S. aureus that possesses a locus encoding iron-regulated surface determinant (Isd) proteins involved in iron acquisition from haemoglobin.
MeSH terms
Bacterial Proteins; Base Sequence; Genome, Bacterial; Humans; Molecular Sequence Data; Staphylococcal Infections; Staphylococcus lugdunensis; Virulence Factors
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