Outbreak of pandemic influenza A/H1N1 2009 in Nepal.
Virol J, 2011/3/23;8:133.
Adhikari BR[1], Shakya G, Upadhyay BP, Prakash Kc K, Shrestha SD, Dhungana GR
Affiliations
PMID: 21426589DOI: 10.1186/1743-422X-8-133
Impact factor: 5.913
Abstract
background: The 2009 flu pandemic is a global outbreak of a new strain of H1N1 influenza virus. Pandemic influenza A (H1N1) 2009 has posed a serious public health challenge world-wide. Nepal has started Laboratory diagnosis of Pandemic influenza A/H1N1 from mid June 2009 though active screening of febrile travellers with respiratory symptoms was started from April 27, 2009.
results: Out of 609 collected samples, 302 (49.6%) were Universal Influenza A positive. Among the influenza A positive samples, 172(28.3%) were positive for Pandemic influenza A/H1N1 and 130 (21.3%) were Seasonal influenza A. Most of the pandemic cases (53%) were found among young people with ≤ 20 years. Case Fatality Ratio for Pandemic influenza A/H1N1 in Nepal was 1.74%. Upon Molecular characterization, all the isolated pandemic influenza A/H1N1 2009 virus found in Nepal were antigenically and genetically related to the novel influenza A/CALIFORNIA/07/2009-LIKE (H1N1)v type.
conclusion: The Pandemic 2009 influenza virus found in Nepal were antigenically and genetically related to the novel A/CALIFORNIA/07/2009-LIKE (H1N1)v type.
MeSH terms
Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Disease Outbreaks; Female; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza, Human; Male; Middle Aged; Molecular Sequence Data; Nepal; Pandemics; Phylogeny; Young Adult
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